Verification: Pharmacokinetic reviews confirm that intranasal delivery utilizes the olfactory and trigeminal nerve pathways
SURMOUNT-1 Trial (NEJM, 2022): Tirzepatide up to 20.9% weight loss
Jeffs hemoglobin A1C dropped from 10.1% to 6% over 3 months, which was very promising
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This way we could also quantify and statistically test the difference of each Treatment condition (including the Baseline and Vehicle controls) from the daily nutritional recommendation